Difference between revisions of "Transcription factors and their control"

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(→‎Transcription factors/ other)
(→‎Transcription factors/ other)
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Revision as of 08:45, 21 August 2013

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Transcription factors control gene expression by regulating transcription initiation or transcription elongation. Transcription initiation is regulated by DNA-binding proteins, whereas transcription elongation can be controlled by DNA-binding proteins ("transcriptional roadblocks") or RNA-binding proteins (transcription termination/ antitermination).

Transcription factors can be grouped according to their mode of interaction with nucleic acids (DNA-or RNA-binding proteins) and also according to the mechanism by which they perceive the signal.

DNA-binding transcription factors

RNA-binding transcription factors

Transcription factors according to signal perception

Reviews on transcription regulation

Semen A Leyn, Marat D Kazanov, Natalia V Sernova, Ekaterina O Ermakova, Pavel S Novichkov, Dmitry A Rodionov
Genomic reconstruction of the transcriptional regulatory network in Bacillus subtilis.
J Bacteriol: 2013, 195(11);2463-73
[PubMed:23504016] [WorldCat.org] [DOI] (I p)

Julio A Freyre-González, Luis G Treviño-Quintanilla, Ilse A Valtierra-Gutiérrez, Rosa María Gutiérrez-Ríos, José A Alonso-Pavón
Prokaryotic regulatory systems biology: Common principles governing the functional architectures of Bacillus subtilis and Escherichia coli unveiled by the natural decomposition approach.
J Biotechnol: 2012, 161(3);278-86
[PubMed:22728391] [WorldCat.org] [DOI] (I p)

Lakshminarayan M Iyer, L Aravind
Insights from the architecture of the bacterial transcription apparatus.
J Struct Biol: 2012, 179(3);299-319
[PubMed:22210308] [WorldCat.org] [DOI] (I p)

Sacha A F T van Hijum, Marnix H Medema, Oscar P Kuipers
Mechanisms and evolution of control logic in prokaryotic transcriptional regulation.
Microbiol Mol Biol Rev: 2009, 73(3);481-509, Table of Contents
[PubMed:19721087] [WorldCat.org] [DOI] (I p)

Sarath Chandra Janga, Ernesto Pérez-Rueda
Plasticity of transcriptional machinery in bacteria is increased by the repertoire of regulatory families.
Comput Biol Chem: 2009, 33(4);261-8
[PubMed:19632156] [WorldCat.org] [DOI] (I p)

P J Lewis, G P Doherty, J Clarke
Transcription factor dynamics.
Microbiology (Reading): 2008, 154(Pt 7);1837-1844
[PubMed:18599813] [WorldCat.org] [DOI] (P p)

Samadhi Moreno-Campuzano, Sarath Chandra Janga, Ernesto Pérez-Rueda
Identification and analysis of DNA-binding transcription factors in Bacillus subtilis and other Firmicutes--a genomic approach.
BMC Genomics: 2006, 7;147
[PubMed:16772031] [WorldCat.org] [DOI] (I e)


Genes in this functional category

Two-component system response regulators

Control of two-component response regulators

Two-component sensor kinase

Response regulator aspartate phosphatase

Control of response regulators/ other

PRD-type regulators

Control of PRD-type regulators

Transcription factors/ other

Transcription factor/ other/ based on similarity

Control of transcription factor (other than two-component system)

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