treR

treR
168

transcription repressor of the treP-treA-treR operon (GntR family)

Locus
BSU_07820
Molecular weight
27.69 kDa
Isoelectric point
6.82
Protein length
238 aaSequenceBlast
Gene length
717 bpSequenceBlast
Function
regulation of trehalose utilization
Product
transcription repressor (GntR family)
Essential
no
Synonyms
treR, yfxA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2188 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
853,556 → 854,272
The protein
Protein family
GntR family of transcription factors
Domains
HTH gntR-type domain (aa 1-71) (according to UniProt)
Structure
2OGG (PDB) (effector binding domain) PubMed
P39796 (AlphaFold)
Paralogous protein(s)
YmfC, GamR, NagR, YydK, GmuR, FrlR
Expression and Regulation
Operons
Genes
treP-treA-treR
Description
PubMed
Regulation
expressed under conditions of phosphate limitation (PhoP) PubMed
Regulatory mechanism
TreR: repression, PubMed, in treR regulon
CcpA: repression, PubMed, in ccpA regulon
PhoP: activation, PubMed, in phoP regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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treP→treR

2025-03-17 20:06:09

ghost

96

5ea0c439875fc22b9a05971658c7c0a460d25052

9C91E3C2B12C6666EE92EE6C971F82C82DDCB383

Biological materials
Mutant
MGNA-C261 (treR::erm), available at the NBRP B. subtilis, Japan
BKE07820 (ΔtreR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTATGGACCACCCAGCTT,  downstream forward: _UP4_TGAGAGAGGCGCCTGCCTGC
BKK07820 (ΔtreR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTATGGACCACCCAGCTT,  downstream forward: _UP4_TGAGAGAGGCGCCTGCCTGC
References
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Time of last update: 2025-04-02 18:04:17

Author of last update: Jstuelk