ascR

ascR
168

alkyl-sulphur catabolism regulator, transcriptional activator of the snaA-tcyJ-tcyK-tcyL-tcyM-tcyN-cmoO-cmoI-cmoJ-ribR-sndA-ytnM operon

Locus
BSU_29400
Molecular weight
35.08 kDa
Isoelectric point
6.23
Protein length
308 aaSequenceBlast
Gene length
927 bpSequenceBlast
Function
regulation of sulphur metabolism
Product
alkyl-sulphur catabolism regulator, transcriptional activator (LysR family)
Essential
no
Synonyms
ascR, ytlI
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0583 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,008,938  3,009,864
The protein
Protein family
LysR family (according to UniProt)
Domains
HTH lysR-type domain (aa 1-57) (according to UniProt)
Structure
O35038 (AlphaFold)
Expression and Regulation
Operons
Genes
ascR
Description
PubMed
Regulation
repressed in the presence of cysteine (CymR) PubMed
Regulatory mechanism
CymR: repression, PubMed, in cymR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

ascR

2025-03-15 23:07:03

ghost

75

5b5203b71dca960edda27cc341d540816c9f11ef

9DFC86E3C6650FB912B4F5A401D5BCDF518B4C4B

Biological materials
Mutant
GP4472 (trpC2 ΔacsR::neo), available in Jörg Stülke's lab
MGNA-A169 (ytlI::erm), available at the NBRP B. subtilis, Japan
BKE29400 (ascR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATGTGCTCCCTCCTGTTT,  downstream forward: _UP4_TAACTGAAAAAATAAAAACC
BKK29400 (ascR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATGTGCTCCCTCCTGTTT,  downstream forward: _UP4_TAACTGAAAAAATAAAAACC
References
Loading

741156D495BE3857683C8A0390764EAD83845ABC

Page visits: 5464

Time of last update: 2025-03-31 17:45:13

Author of last update: Robert.warneke