Genetic competence

Parent categories	4. Lifestyles 4.1. Exponential and early post-exponential lifestyles
Neighbouring categories	4.1.1. Motility and chemotaxis 4.1.2. Swarming 4.1.3. Sliding 4.1.4. Biofilm formation 4.1.5. Genetic competence
Related categories	DNA repair/ recombination ComA regulon ComK regulon
Overview on the categories (Excel file) All genes and their categories (Excel file)

Parent categories	3. Information processing 3.1. Genetics
Neighbouring categories	3.1.1. DNA replication 3.1.2. DNA condensation/ segregation 3.1.3. DNA restriction/ modification 3.1.4. DNA repair/ recombination 3.1.5. Genetic competence 3.1.6. Genetics/ other
Related categories	DNA repair/ recombination ComA regulon ComK regulon
Overview on the categories (Excel file) All genes and their categories (Excel file)

• The wild type strain NCIB3610 is only poorly competent because the small protein ComI encoded on the endogenous plasmid pBS32 inhibits the competence DNA uptake machinery. PubMed

Labs working on genetic competence

• David Dubnau
• Oscar Kuipers

Genes in this functional category

• addA
• addB
• bdbC
• bdbD
• coiA
• comA
• comC
• comEA
• comEB
• comEC
• comER
• comFA
• comFB
• comFC
• comGA
• comGB
• comGC
• comGD
• comGE
• comGF
• comGG
• comK
• comN
• comP
• comQ
• comS
• comX
• comZ
• dprA
• kre
• maf
• mecA
• med
• nin
• nucA
• oppA
• oppB
• oppC
• oppD
• oppF
• phrC
• phrF
• phrK
• pnpA
• radC
• rapC
• rapD
• rapF
• rapK
• recA
• rok
• sbcC
• sbcD
• ssbB
• yidC2
• yvcJ

Important original publications

Andrew Mugler, Mark Kittisopikul, Luke Hayden, Jintao Liu, Chris H Wiggins, Gürol M Süel, Aleksandra M Walczak
Noise Expands the Response Range of the Bacillus subtilis Competence Circuit.
PLoS Comput Biol: 2016, 12(3);e1004793
[PubMed:27003682] [WorldCat.org] [DOI] (I e)

Hongguang Xi, Zhuoqin Yang, Marc Turcotte
Subtle interplay of stochasticity and deterministic dynamics pervades an evolutionary plausible genetic circuit for Bacillus subtilis competence.
Math Biosci: 2013, 246(1);148-63
[PubMed:24012503] [WorldCat.org] [DOI] (I p)

Melissa A Konkol, Kris M Blair, Daniel B Kearns
Plasmid-encoded ComI inhibits competence in the ancestral 3610 strain of Bacillus subtilis.
J Bacteriol: 2013, 195(18);4085-93
[PubMed:23836866] [WorldCat.org] [DOI] (I p)