comFB

comFB
168

late competence gene, c-di-GMP-binding protein

Locus
BSU_35460
Molecular weight
10.84 kDa
Isoelectric point
4.83
Protein length
98 aaSequenceBlast
Gene length
297 bpSequenceBlast
Function
compentence
Product
unknown
Essential
no
Synonyms
comFB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
3,641,811 → 3,642,107
The protein
Cofactors
Zn2+ PubMed
Structure
4WAI (PDB) PubMed
P39146 (AlphaFold)
Effectors of protein activity
binds c-di-GMP, KD: 0.17 μM PubMed
Localization
forms dimers PubMed
cytoplasma PubMed
localizes to one or both cell poles PubMed
Expression and Regulation
Operons
Genes
comFA-comFB-comFC-yvyF-flgM-flgN-flgK-flgL-yviE-fliW-csrA
Description
PubMed
Expression
expression is heterogeneous PubMed
Regulatory mechanism
ComK: activation, PubMed, in comK regulon
DegU: activation, DegU-P, PubMed, in degU regulon
ScoC: repression, PubMed, in scoC regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigD: sigma factor, PubMed, in sigD regulon
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comFA→csrA

2025-03-28 01:21:10

Jstuelk

156

F13A7084BCCB15345BC26C03AF15EE753EFDF196

11180672E46D33F7D747E58441ECB10AEE7F8D8B

Biological materials
Mutant
GP4446 (trpC2 ΔcomFB::neo), available in Jörg Stülke's lab
BKE35460 (ΔcomFB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTTACAGCTCCTCATC,  downstream forward: _UP4_AAGCAGGAGGAGGCATTCAT
BKK35460 (ΔcomFB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTTACAGCTCCTCATC,  downstream forward: _UP4_AAGCAGGAGGAGGCATTCAT
References
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D290247A43280532947B707F3AF388D7A7F404D3

Page visits: 5256

Time of last update: 2025-03-30 03:41:37

Author of last update: Jstuelk