AccD
Revision as of 12:27, 6 June 2014 by Fabian Commichau (talk | contribs)
- Description: acetyl-CoA carboxylase (beta subunit)
Gene name | accD |
Synonyms | yttI |
Essential | yes PubMed |
Product | acetyl-CoA carboxylase (beta subunit)) |
Function | production of malonyl-CoA, the substrate for fatty acid biosynthesis |
Gene expression levels in SubtiExpress: accD | |
Interactions involving this protein in SubtInteract: AccD | |
Metabolic function and regulation of this protein in SubtiPathways: accD | |
MW, pI | 32 kDa, 5.344 |
Gene length, protein length | 873 bp, 290 aa |
Immediate neighbours | accA, ytsJ |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
biosynthesis of lipids, essential genes, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29210
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU29210
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- phosphorylated on Arg-205 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization: Membrane-proximal (Spotty) PubMed Membrane-proximal (Spotty) PubMed
Database entries
- BsubCyc: BSU29210
- UniProt: C0SP93
- KEGG entry: [3]
- E.C. number: 6.4.1.2
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Stephen W White, Jie Zheng, Yong-Mei Zhang, Rock
The structural biology of type II fatty acid biosynthesis.
Annu Rev Biochem: 2005, 74;791-831
[PubMed:15952903]
[WorldCat.org]
[DOI]
(P p)
John E Cronan, Grover L Waldrop
Multi-subunit acetyl-CoA carboxylases.
Prog Lipid Res: 2002, 41(5);407-35
[PubMed:12121720]
[WorldCat.org]
[DOI]
(P p)
Original Publications