PksG

• Description: involved in polyketide synthesis
  
  

Gene name	pksG
Synonyms
Essential	no
Product	hydroxymethylglutaryl CoA synthase
Function	polyketide synthesis
Gene expression levels in SubtiExpress: pksG
MW, pI	46 kDa, 5.137
Gene length, protein length	1260 bp, 420 aa
Immediate neighbours	pksF, pksH
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

AbrB regulon, CodY regulon

The gene

Basic information

• Locus tag: BSU17150

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: HMG-CoA synthase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P40830

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: pksC-pksD-pksE-acpK-pksF-pksG-pksH-pksI-pksJ-pksL-pksM-pksN-pksR PubMed

• Expression browser: pksG PubMed

• Sigma factor:

• Regulation:
  • expressed during the transition from growth to stationary phase (AbrB, CodY) PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed
  • CodY: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: