SpoIIAB

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Gene name spoIIAB
Synonyms
Essential no
Product anti-SigF/ protein serine kinase
Function control of SigF activity
septation; phosphorylation and inactivation of SpoIIAA
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 16 kDa, 4.383
Gene length, protein length 438 bp, 146 aa
Immediate neighbours sigF, spoIIAA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpoIIAB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU23460

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

protein modification, sigma factors and their control, sporulation proteins

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + a protein = ADP + a phosphoprotein (according to Swiss-Prot)
  • Protein family: anti-sigma-factor family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure: 1L0O (complex with SigF, Geobacillus stearothermophilus), 1TIL (complex with SpoIIAA, Geobacillus stearothermophilus)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • dacF: expressed during sporulation
    • spoIIAA: expressed early during sporulation
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References