Difference between revisions of "TkmA"

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* '''Description:''' transmembrane modulator of [[PtkA]] activity, activates [[PtkA]] autophosphorylation and substrate phosphorylation <br/><br/>
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* '''Description:''' transmembrane modulator of [[PtkA]] activity, activates [[PtkA]] autophosphorylation and substrate phosphorylation &lt;br/>&lt;br/>
  
 
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ptkA]]'', ''[[ywqB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ptkA]]'', ''[[ywqB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15643&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&amp;#91;EMBLCDS:CAB15643&amp;#93;+-newId sequences] &lt;br/> (Barbe ''et al.'', 2009)'''
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ywqC_context.gif]]
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|colspan="2" | '''Genetic context''' &lt;br/> [[Image:ywqC_context.gif]]
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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  &lt;div align="right"> &lt;small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]&lt;/small>&lt;/div>
 
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__TOC__
 
__TOC__
  
<br/><br/>
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&lt;br/>&lt;br/>
  
 
=The gene=
 
=The gene=
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=References=
 
=References=
  
<pubmed>12970183, 20815827 20817675</pubmed>
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&lt;pubmed>12970183, 20815827 20817675&lt;/pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 23:23, 23 November 2010



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  • Description: transmembrane modulator of PtkA activity, activates PtkA autophosphorylation and substrate phosphorylation <br/><br/>
Gene name tkmA
Synonyms ywqC
Essential no
Product modulator of PtkA activity
Function control of protein tyrosine phosphorylation
MW, pI 26 kDa, 4.61
Gene length, protein length 744 bp, 248 aa
Immediate neighbours ptkA, ywqB
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> YwqC context.gif
<div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/>

The gene

Basic information

  • Locus tag: BSU36260

Phenotypes of a mutant

the mutant exhibits a defect in biofilm formation PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transmembrane activation of PtkA protein tyrosine kinase activity
  • Protein family: cpsC/capA family (according to Swiss-Prot)
  • Paralogous protein(s): EpsA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

<pubmed>12970183, 20815827 20817675</pubmed>