Difference between revisions of "RNA polymerase"

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=== Important original publications ===
 
=== Important original publications ===
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<pubmed> 21350489 21515770 22333917,20817769,20724389,21710567 23761441 23875654 23771146 24789973 25961799 26400263  27622946  27977677 29454936 31548377 32848247 33243850,36972428, 37949068 </pubmed>

Latest revision as of 17:54, 20 November 2023

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The enzyme responsible for transcription

  • As an important difference as compared to the E. coli enzyme, the B. subtilis RNA polymerase has a strong preference for G as first nucleotides in transcripts PubMed

Components of the RNA polymerase

Core subunits

Sigma factors

  • In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)

Small accessory subunits

  • RpoE: delta subunit
  • RpoY: epsilon subunit
  • YloH: omega subunit

Other interaction partners

Temporary interaction partners

  • Spx: transcription regulator, interacts with RpoA
  • MgsR: transcription regulator orthologous to Spx, interacts with RpoA
  • Btr: transcription activator PubMed
  • YlyA: modulates SigG-dependent transcription PubMed

Back to protein-protein interactions

References

Reviews


The structure of RNA polymerase


Important original publications