Difference between revisions of "CtpB"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | + | ** substrate binding of CtpB induces opening of the PDZ gate and protease activation {{PubMed|24243021}} | |
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| + | ** intracellular space between the mother cell and the forespore {{PubMed|24243021}} | ||
=== Database entries === | === Database entries === | ||
* '''Structure:''' | * '''Structure:''' | ||
| + | ** forms a ring-like scaffold with two narrow tunnels for substrate binding {{PubMed|24243021}} | ||
* '''UniProt:''' [http://www.uniprot.org/uniprot/O35002 O35002] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O35002 O35002] | ||
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=References= | =References= | ||
| − | <pubmed>14526016, 17557826, 16818230 15699190,16497325</pubmed> | + | <pubmed>14526016, 17557826, 16818230 15699190,16497325 24243021 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:43, 3 December 2013
- Description: carboxy-terminal processing serine protease, cleaves SpoIVFA, this results in processing of pro-SigK
| Gene name | ctpB |
| Synonyms | yvjB |
| Essential | no |
| Product | carboxy-terminal processing serine protease, cleaves SpoIVFA |
| Function | control of SigK activation |
| Gene expression levels in SubtiExpress: ctpB | |
| MW, pI | 52 kDa, 8.641 |
| Gene length, protein length | 1440 bp, 480 aa |
| Immediate neighbours | swrAA/2, ftsX |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
proteolysis, sigma factors and their control, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35240
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): CtpA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Effectors of protein activity:
- substrate binding of CtpB induces opening of the PDZ gate and protease activation PubMed
- Interactions:
- Localization:
- intracellular space between the mother cell and the forespore PubMed
Database entries
- Structure:
- forms a ring-like scaffold with two narrow tunnels for substrate binding PubMed
- UniProt: O35002
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ctpB (according to DBTBS)
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
