Difference between revisions of "AccD"

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= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[biosynthesis of lipids]]}},
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{{SubtiWiki category|[[essential genes]]}}
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= This gene is a member of the following [[regulons]] =
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{{SubtiWiki regulon|[[Spo0A regulon]]}}
  
 
=The gene=
 
=The gene=
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[biosynthesis of lipids]]}},
 
{{SubtiWiki category|[[essential genes]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 22:22, 8 December 2010

  • Description: acetyl-CoA carboxylase (beta subunit)

Gene name accD
Synonyms yttI
Essential yes PubMed
Product acetyl-CoA carboxylase (beta subunit))
Function production of malonyl-CoA, the substrate for fatty acid biosynthesis
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis
MW, pI 28 kDa, 5.344
Gene length, protein length 786 bp, 262 aa
Immediate neighbours accA, ytsJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AccD context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

biosynthesis of lipids, essential genes

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU29210

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: Membrane-proximal (Spotty) PubMed Membrane-proximal (Spotty) PubMed

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Stephen W White, Jie Zheng, Yong-Mei Zhang, Rock
The structural biology of type II fatty acid biosynthesis.
Annu Rev Biochem: 2005, 74;791-831
[PubMed:15952903] [WorldCat.org] [DOI] (P p)

Original Publications