Difference between revisions of "Biosynthesis of cofactors"

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=== Biosynthesis/ acquisition of riboflavin/ fad ===  
 
=== Biosynthesis/ acquisition of riboflavin/ fad ===  
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* [[ribA]]
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* ''[[ribA]]''
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* [[ribC]]
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* ''[[ribC]]''
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* [[ribD]]
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* ''[[ribD]]''
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* [[ribE]]
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* ''[[ribE]]''
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* [[ribH]]
+
* ''[[ribH]]''
−
* [[ribT]]
+
* ''[[ribR]]''
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* [[ribU]]
+
* ''[[ribT]]''
 +
* ''[[ribU]]''
 +
* ''[[ycsE]]''
  
 
=== Biosynthesis/ acquisition of thiamine ===  
 
=== Biosynthesis/ acquisition of thiamine ===  
 
* [[dxs]]
 
* [[dxs]]
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* [[nifZ]]
 
 
* [[tenA]]
 
* [[tenA]]
 
* [[tenI]]
 
* [[tenI]]
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* [[ylmB]]
 
* [[ylmB]]
 
* [[yloS]]
 
* [[yloS]]
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=== Biosynthesis/ acquisition of thiamine/ based on similarity ===
 
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* [[ytbJ]]
 
  
 
=== Biosynthesis of coenzyme a ===  
 
=== Biosynthesis of coenzyme a ===  
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* [[ylnF]]
 
* [[ylnF]]
  
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=== Biosynthesis of lipoic acid ===  
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=== Biosynthesis of lipoic acid (For complete biosynthetic pathway see {{PubMed|21338421}}) ===  
 
* [[lipA]]
 
* [[lipA]]
 
* [[lipM]]
 
* [[lipM]]
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* [[moeA]]
 
* [[moeA]]
 
* [[moeB]]
 
* [[moeB]]
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* [[ydiG]]
  
 
=== Biosynthesis of nad(p) ===  
 
=== Biosynthesis of nad(p) ===  
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* [http://subtiwiki.uni-goettingen.de/pathways/biotin/index.html Biotin synthesis]
 
* [http://subtiwiki.uni-goettingen.de/pathways/biotin/index.html Biotin synthesis]
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 +
==Important original publications==
 +
<pubmed> 24972371 28196402</pubmed>
  
 
==Important reviews==
 
==Important reviews==
−
'''Additional reviews:''' {{PubMed|21437340}}
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<pubmed> 11153271 22616866 19348578 18314013 14675553 10382260 24442413 21646432,21437340 26758294 27074917    27890703</pubmed>
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<pubmed> 11153271 21646432 22616866 </pubmed>
 
−
<pubmed> 19348578 18314013 14675553 10382260 </pubmed>
 
  
 
=Back to [[categories]]=
 
=Back to [[categories]]=

Latest revision as of 16:58, 15 February 2017

Parent categories
Neighbouring categories
Related categories

Genes in this functional category

Biosynthesis/ acquisition of biotin

Biosynthesis/ acquisition of riboflavin/ fad

Biosynthesis/ acquisition of thiamine

Biosynthesis of coenzyme a

Biosynthesis of folate

Biosynthesis of heme/ siroheme

Biosynthesis of lipoic acid (For complete biosynthetic pathway see PubMed)

Biosynthesis of menaquinone

Biosynthesis of menaquinone/ based on similarity

Biosynthesis of molybdopterin

Biosynthesis of nad(p)

Biosynthesis of pyridoxal phosphate

Metabolism of cofactors in SubtiPathways

Important original publications

Miglena Manandhar, John E Cronan
Pimelic acid, the first precursor of the Bacillus subtilis biotin synthesis pathway, exists as the free acid and is assembled by fatty acid synthesis.
Mol Microbiol: 2017, 104(4);595-607
[PubMed:28196402] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Ariane Alzinger, Rafael Sande, Werner Bretzel, Frederik M Meyer, Bastien Chevreux, Markus Wyss, Hans-Peter Hohmann, Zoltán Prágai
Overexpression of a non-native deoxyxylulose-dependent vitamin B6 pathway in Bacillus subtilis for the production of pyridoxine.
Metab Eng: 2014, 25;38-49
[PubMed:24972371] [WorldCat.org] [DOI] (I p)


Important reviews

Jonathan Rosenberg, Till Ischebeck, Fabian M Commichau
Vitamin B6 metabolism in microbes and approaches for fermentative production.
Biotechnol Adv: 2017, 35(1);31-40
[PubMed:27890703] [WorldCat.org] [DOI] (I p)

John E Cronan
Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway.
Microbiol Mol Biol Rev: 2016, 80(2);429-50
[PubMed:27074917] [WorldCat.org] [DOI] (I e)

Susanne Katharina Schwechheimer, Enoch Y Park, José Luis Revuelta, Judith Becker, Christoph Wittmann
Biotechnology of riboflavin.
Appl Microbiol Biotechnol: 2016, 100(5);2107-19
[PubMed:26758294] [WorldCat.org] [DOI] (I p)

Markus Birkenmeier, Susanne Neumann, Thorsten Röder
Kinetic modeling of riboflavin biosynthesis in Bacillus subtilis under production conditions.
Biotechnol Lett: 2014, 36(5);919-28
[PubMed:24442413] [WorldCat.org] [DOI] (I p)

Tadhg P Begley, Steven E Ealick, Fred W McLafferty
Thiamin biosynthesis: still yielding fascinating biological chemistry.
Biochem Soc Trans: 2012, 40(3);555-60
[PubMed:22616866] [WorldCat.org] [DOI] (I p)

Charles A Abbas, Andriy A Sibirny
Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers.
Microbiol Mol Biol Rev: 2011, 75(2);321-60
[PubMed:21646432] [WorldCat.org] [DOI] (I p)

Steven Lin, John E Cronan
Closing in on complete pathways of biotin biosynthesis.
Mol Biosyst: 2011, 7(6);1811-21
[PubMed:21437340] [WorldCat.org] [DOI] (I p)

Christopher T Jurgenson, Tadhg P Begley, Steven E Ealick
The structural and biochemical foundations of thiamin biosynthesis.
Annu Rev Biochem: 2009, 78;569-603
[PubMed:19348578] [WorldCat.org] [DOI] (I p)

Tadhg P Begley, Abhishek Chatterjee, Jeremiah W Hanes, Amrita Hazra, Steven E Ealick
Cofactor biosynthesis--still yielding fascinating new biological chemistry.
Curr Opin Chem Biol: 2008, 12(2);118-25
[PubMed:18314013] [WorldCat.org] [DOI] (P p)

Ethan Settembre, Tadhg P Begley, Steven E Ealick
Structural biology of enzymes of the thiamin biosynthesis pathway.
Curr Opin Struct Biol: 2003, 13(6);739-47
[PubMed:14675553] [WorldCat.org] [DOI] (P p)

A Marquet, B T Bui, D Florentin
Biosynthesis of biotin and lipoic acid.
Vitam Horm: 2001, 61;51-101
[PubMed:11153271] [WorldCat.org] [DOI] (P p)

T P Begley, D M Downs, S E Ealick, F W McLafferty, A P Van Loon, S Taylor, N Campobasso, H J Chiu, C Kinsland, J J Reddick, J Xi
Thiamin biosynthesis in prokaryotes.
Arch Microbiol: 1999, 171(5);293-300
[PubMed:10382260] [WorldCat.org] [DOI] (P p)


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