Difference between revisions of "ThiS"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU11680&redirect=T BSU11680]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/tenAI-goxB-thiSGF-yjbV.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/tenAI-goxB-thiSGF-yjbV.html]
Line 96: Line 97:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU11680&redirect=T BSU11680]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=1TYG 1TYG] (complex with [[ThiG]]) {{PubMed|15362849}}
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=1TYG 1TYG] (complex with [[ThiG]]) {{PubMed|15362849}}

Revision as of 13:25, 2 April 2014

  • Description: sulfur carrier protein, hydroxyethylthiazole phosphate biosynthesis

Gene name thiS
Synonyms yjbS
Essential no
Product sulfur carrier protein
Function biosynthesis of thiamine
Gene expression levels in SubtiExpress: thiS
Interactions involving this protein in SubtInteract: ThiS
Metabolic function and regulation of this protein in SubtiPathways:
thiS
MW, pI 7 kDa, 5.501
Gene length, protein length 198 bp, 66 aa
Immediate neighbours thiO, thiG
Sequences Protein DNA DNA_with_flanks
Genetic context
ThiS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ThiS expression.png




























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

Thi-box

The gene

Basic information

  • Locus tag: BSU11680

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Christopher T Jurgenson, Tadhg P Begley, Steven E Ealick
The structural and biochemical foundations of thiamin biosynthesis.
Annu Rev Biochem: 2009, 78;569-603
[PubMed:19348578] [WorldCat.org] [DOI] (I p)

T P Begley, D M Downs, S E Ealick, F W McLafferty, A P Van Loon, S Taylor, N Campobasso, H J Chiu, C Kinsland, J J Reddick, J Xi
Thiamin biosynthesis in prokaryotes.
Arch Microbiol: 1999, 171(5);293-300
[PubMed:10382260] [WorldCat.org] [DOI] (P p)

Original publications