Difference between revisions of "PksC"

From SubtiWiki
Jump to: navigation, search
Line 35: Line 35:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
 
 
<br/><br/>
 
<br/><br/>
  
Line 78: Line 74:
 
* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
Line 104: Line 100:
 
=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' [[pksC]]-[[pksD]]-[[pksE]]-[[acpK]]-[[pksF]]-[[pksG]]-[[pksH]]-[[pksI]]-[[pskJ]]-[[pksL]]-[[pksM]]-[[pksN]]-[[pksR]] {{PubMed|22383849}}
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pksC_1783763_1784629_1 pksC] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pksC_1783763_1784629_1 pksC] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** expressed during the transition from growth to stationary phase ([[AbrB]], [[CodY]]) {{PubMed|24187085}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[AbrB]]: transcription repression {{PubMed|24187085}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
 +
** this is a very large operon comprising about 75 kb
  
 
=Biological materials =
 
=Biological materials =
Line 135: Line 134:
  
 
=References=
 
=References=
'''Additional publications:''' {{PubMed|21505242}}
+
<pubmed>22383849 21505242 24187085</pubmed>  
<pubmed></pubmed>  
 
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:17, 17 December 2013

  • Description: bacillaene synthase trans-acting acyltransferase

Gene name pksC
Synonyms
Essential no
Product bacillaene synthase trans-acting acyltransferase
Function polyketide (bacillaene) synthesis
Gene expression levels in SubtiExpress: pksC
MW, pI 32 kDa, 5.328
Gene length, protein length 864 bp, 288 aa
Immediate neighbours pksB, pksD
Sequences Protein DNA DNA_with_flanks
Genetic context
PksC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PksC expression.png















Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17100

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed during the transition from growth to stationary phase (AbrB, CodY) PubMed
  • Regulatory mechanism:
  • Additional information:
    • this is a very large operon comprising about 75 kb

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References