Difference between revisions of "RNA polymerase"

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=='''The enzyme responsible for [[transcription]]'''==
 
=='''The enzyme responsible for [[transcription]]'''==
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* As an important difference as compared to the ''E. coli'' enzyme, the ''B. subtilis'' RNA polymerase has a strong preference for G as first nucleotides in transcripts {{PubMed|23761441}}
  
 
==Components of the RNA polymerase==
 
==Components of the RNA polymerase==
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<pubmed> 12732296 12581657 11297923 19735077 </pubmed>
 
<pubmed> 12732296 12581657 11297923 19735077 </pubmed>
 
=== Important original publications ===
 
=== Important original publications ===
<pubmed> 21350489 21515770 22333917,20817769,20724389,21710567</pubmed>
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<pubmed> 21350489 21515770 22333917,20817769,20724389,21710567 23761441 </pubmed>

Revision as of 14:10, 14 June 2013

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The enzyme responsible for transcription

  • As an important difference as compared to the E. coli enzyme, the B. subtilis RNA polymerase has a strong preference for G as first nucleotides in transcripts PubMed

Components of the RNA polymerase

Core subunits

Sigma factors

  • In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)

Small accessory subunits

  • RpoE: delta subunit
  • YkzG: epsilon subunit
  • YloH: omega subunit

Other interaction partners

Temporary interaction partners

  • Spx: transcription regulator, interacts with RpoA
  • MgsR: transcription regulator orthologous to Spx, interacts with RpoA
  • Btr: transcription activator PubMed
  • YlyA: modulates SigG-dependent transcription PubMed

Back to protein-protein interactions

References

Reviews


The structure of RNA polymerase

Important original publications