Difference between revisions of "CdaS"
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|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''cdaS'' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yojJ '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
| Line 14: | Line 14: | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of c-di-AMP | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of c-di-AMP | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU19430 | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU19430 cdaS] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.367 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.367 | ||
| Line 105: | Line 105: | ||
* '''Operon:''' | * '''Operon:''' | ||
| − | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yojJ_2118504_2119127_-1 | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yojJ_2118504_2119127_-1 cdaS] {{PubMed|22383849}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigG]] {{PubMed|22383849}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed late during sporulation in the forespore ([[SigG]]) {{PubMed|22383849}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 139: | Line 140: | ||
<pubmed> 18714086</pubmed> | <pubmed> 18714086</pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>21566650, 23192352 </pubmed> | + | <pubmed>21566650, 23192352 22383849</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:56, 30 November 2012
- Description: sporulation-specific diadenylate cyclase, synthesis of c-di-AMP
| Gene name | cdaS |
| Synonyms | yojJ |
| Essential | no |
| Product | sporulation-specific diadenylate cyclase |
| Function | synthesis of c-di-AMP |
| Gene expression levels in SubtiExpress: cdaS | |
| MW, pI | 22 kDa, 5.367 |
| Gene length, protein length | 621 bp, 207 aa |
| Immediate neighbours | yojK, yojI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
metabolism of signalling nucleotides, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU19430
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- synthesis of c-di-AMP from two molecules of ATP PubMed
- Protein family:
- Paralogous protein(s): CdaA
Extended information on the protein
- Kinetic information:
- Domains: contains a DAC domain involved in the synthesis of c-di-AMP PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 2FB5 (the protein of B. cereus, 48% identity, 81% similarity)
- UniProt: O31854
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- GP983 (yojJ::ermC), available in Jörg Stülke's lab
- GP1360 (yojJ::spc), available in Jörg Stülke's lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications
