Difference between revisions of "SpoIVB"
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| − | * '''Description:''' serine protease, cleaves [[SpoIVFA]], this results in pro- | + | * '''Description:''' serine protease, cleaves [[SpoIVFA]], this results in pro-[[SigK]] processing/activation in the mother-cell, does also cleave [[CtpB]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 90: | Line 90: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''spoIVB'' {{PubMed|2106508}} |
| − | * '''[[Sigma factor]]:''' [[SigF]] {{PubMed|15699190}}, [[SigG]] {{PubMed|15699190}} | + | * '''[[Sigma factor]]:''' [[SigF]] {{PubMed|15699190,9004507}}, [[SigG]] {{PubMed|15699190,9004507}} |
| − | * '''Regulation:''' expressed during sporulation in the forespore ([[SigF]], [[SigG]]) {{PubMed|16497325}} | + | * '''Regulation:''' |
| + | ** expressed during sporulation in the forespore ([[SigF]], [[SigG]], [[SpoVT]]) {{PubMed|16497325,15699190,9004507,8755877}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[SpoVT]]: transcription activation {{PubMed|8755877}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 122: | Line 124: | ||
=References= | =References= | ||
| − | <pubmed>17493131 10931284,14526016,10931291,1900494,11418578,15292188,9004507,12940997,11741860,16497325, | + | <pubmed>17493131 2106508 10931284,14526016,10931291,1900494,11418578, 15292188,9004507,12940997, 11741860,16497325,8755877 ,,15292188, 17557826 16818230 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:54, 20 November 2009
- Description: serine protease, cleaves SpoIVFA, this results in pro-SigK processing/activation in the mother-cell, does also cleave CtpB
| Gene name | spoIVB |
| Synonyms | |
| Essential | no |
| Product | serine protease |
| Function | control of SigK activation |
| MW, pI | 45 kDa, 8.842 |
| Gene length, protein length | 1275 bp, 425 aa |
| Immediate neighbours | spo0A, recN |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU24230
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Self-cleaves 52-Val-|-Asn-53, 62-Ala-|-Phe-63 and 74-Val-|-Thr-75 at the N-terminus of SpoIVB (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P17896
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: spoIVB PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Simon Cutting, London, UK homepage
Your additional remarks
References
