Replisome
The replisome is a protein complex that is required and sufficient for replication of both leading and lagging strands.
PolC-HolA-HolB-DnaX-DnaN-DnaG-DnaC-DnaI-DnaD-SsbA-DnaE-PriA-DnaB PubMed
RecA colocalizes to the replisome in response to endogenous and exogenous DNA damage and in response to damage-independent fork arrest (formation of DNA repair centers), repair center formation depends on RecO and RecR, and is facilitated by RecF and SsbA PubMed
Contents
Related pages
Back to Protein-protein interactions
In vitro reconstitution of the replisome
Reviews
Kevin S Lang, Houra Merrikh
The Clash of Macromolecular Titans: Replication-Transcription Conflicts in Bacteria.
Annu Rev Microbiol: 2018, 72;71-88
[PubMed:29856930]
[WorldCat.org]
[DOI]
(I p)
Thomas R Beattie, Rodrigo Reyes-Lamothe
A Replisome's journey through the bacterial chromosome.
Front Microbiol: 2015, 6;562
[PubMed:26097470]
[WorldCat.org]
[DOI]
(P e)
Charles S McHenry
DNA replicases from a bacterial perspective.
Annu Rev Biochem: 2011, 80;403-36
[PubMed:21675919]
[WorldCat.org]
[DOI]
(I p)
Patrick M Schaeffer, Madeleine J Headlam, Nicholas E Dixon
Protein--protein interactions in the eubacterial replisome.
IUBMB Life: 2005, 57(1);5-12
[PubMed:16036556]
[WorldCat.org]
[DOI]
(P p)
Other important publications
