YsbA

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  • Description: putative anti-holin

Gene name ysbA
Synonyms lrgA
Essential no
Product putative anti-holin
Function unknown
Gene expression levels in SubtiExpress: ysbA
MW, pI 15 kDa, 9.825
Gene length, protein length 438 bp, 146 aa
Immediate neighbours ysbB, lytT
Sequences Protein DNA DNA_with_flanks
Genetic context
YsbA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YsbA expression.png















Categories containing this gene/protein

membrane proteins, proteins of unknown function

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU28910

Phenotypes of a mutant

    • ysbAB mutant is delayed in pellicle formation (Chen et al)
    • ywbHG-yxaKC-ysbAB triple mutant is severely delayed in pellicle formation (Chen et al)

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: LrgA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • ysbAB expression is induced by acetate (Chen et al)
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is substantially stabilized upon depletion of RNase Y PubMed
    • the expression of the ysbA-ysbB operon is strongly increased in a cshA mutant PubMed

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References