CsfB
| Gene name | csfB |
| Synonyms | gin, yaaM |
| Essential | no |
| Product | inhibitor of SigG and SigE |
| Function | control of SigG and SigE activity |
| Gene expression levels in SubtiExpress: csfB | |
| Interactions involving this protein in SubtInteract: CsfB | |
| MW, pI | 7 kDa, 7.671 |
| Gene length, protein length | 192 bp, 64 aa |
| Immediate neighbours | rrnA-5S, xpaC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
sigma factors and their control, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00240
Phenotypes of a mutant
premature activation of SigG PubMed
Database entries
- BsubCyc: BSU00240
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: forespore
Database entries
- BsubCyc: BSU00240
- Structure:
- UniProt: P37534
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: csfB
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Mónica Serrano, JinXin Gao, João Bota, Ashley R Bate, Jeffrey Meisner, Patrick Eichenberger, Charles P Moran, Adriano O Henriques
Dual-specificity anti-sigma factor reinforces control of cell-type specific gene expression in Bacillus subtilis.
PLoS Genet: 2015, 11(4);e1005104
[PubMed:25835496]
[WorldCat.org]
[DOI]
(I e)
Mónica Serrano, Gonçalo Real, Joana Santos, Jorge Carneiro, Charles P Moran, Adriano O Henriques
A negative feedback loop that limits the ectopic activation of a cell type-specific sporulation sigma factor of Bacillus subtilis.
PLoS Genet: 2011, 7(9);e1002220
[PubMed:21935351]
[WorldCat.org]
[DOI]
(I p)
Vasant K Chary, Panagiotis Xenopoulos, Avigdor Eldar, Patrick J Piggot
Loss of compartmentalization of σ(E) activity need not prevent formation of spores by Bacillus subtilis.
J Bacteriol: 2010, 192(21);5616-24
[PubMed:20802044]
[WorldCat.org]
[DOI]
(I p)
Lamya Rhayat, Sandra Duperrier, Rut Carballido-López, Olivier Pellegrini, Patrick Stragier
Genetic dissection of an inhibitor of the sporulation sigma factor sigma(G).
J Mol Biol: 2009, 390(5);835-44
[PubMed:19497328]
[WorldCat.org]
[DOI]
(I p)
Céline Karmazyn-Campelli, Lamya Rhayat, Rut Carballido-López, Sandra Duperrier, Niels Frandsen, Patrick Stragier
How the early sporulation sigma factor sigmaF delays the switch to late development in Bacillus subtilis.
Mol Microbiol: 2008, 67(5);1169-80
[PubMed:18208527]
[WorldCat.org]
[DOI]
(I p)
Vasant K Chary, Panagiotis Xenopoulos, Patrick J Piggot
Expression of the sigmaF-directed csfB locus prevents premature appearance of sigmaG activity during sporulation of Bacillus subtilis.
J Bacteriol: 2007, 189(23);8754-7
[PubMed:17921305]
[WorldCat.org]
[DOI]
(I p)
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
A Decatur, R Losick
Identification of additional genes under the control of the transcription factor sigma F of Bacillus subtilis.
J Bacteriol: 1996, 178(16);5039-41
[PubMed:8759874]
[WorldCat.org]
[DOI]
(P p)
C D Webb, A Decatur, A Teleman, R Losick
Use of green fluorescent protein for visualization of cell-specific gene expression and subcellular protein localization during sporulation in Bacillus subtilis.
J Bacteriol: 1995, 177(20);5906-11
[PubMed:7592342]
[WorldCat.org]
[DOI]
(P p)
