BmrB

• Description: regulatory leader peptide for the control of bmrC-bmrD expression
  
  

Gene name	yheJ
Synonyms
Essential	no
Product	leader peptide
Function	control of bmrC-bmrD expression
Gene expression levels in SubtiExpress: yheJ
MW, pI	6 kDa, 11.08
Gene length, protein length	159 bp, 53 aa
Immediate neighbours	nhaX, bmrC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

proteins of unknown function

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

• Locus tag: BSU09700

Database entries

• BsubCyc: BSU09700

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU09700

• Structure:

• UniProt: O07551

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: bmrB-bmrC-bmrD PubMed

• Expression browser: yheJ PubMed

• Sigma factor:

• Regulation:

bmrB-bmrC-bmrD expression only occurs during the late-exponential and stationary growth stages (AbrB) PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ewoud Reilman, Ruben A T Mars, Jan Maarten van Dijl, Emma L Denham
The multidrug ABC transporter BmrC/BmrD of Bacillus subtilis is regulated via a ribosome-mediated transcriptional attenuation mechanism.
Nucleic Acids Res: 2014, 42(18);11393-407
[PubMed:25217586] [WorldCat.org] [DOI] (I p)

Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675] [WorldCat.org] [DOI] (I p)