BmrB

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  • Description: regulatory leader peptide for the control of bmrC-bmrD expression

Gene name yheJ
Synonyms
Essential no
Product leader peptide
Function control of bmrC-bmrD expression
Gene expression levels in SubtiExpress: yheJ
MW, pI 6 kDa, 11.08
Gene length, protein length 159 bp, 53 aa
Immediate neighbours nhaX, bmrC
Sequences Protein DNA DNA_with_flanks
Genetic context
YheJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YheJ expression.png















Categories containing this gene/protein

proteins of unknown function

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

  • Locus tag: BSU09700

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:

bmrB-bmrC-bmrD expression only occurs during the late-exponential and stationary growth stages (AbrB) PubMed

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ewoud Reilman, Ruben A T Mars, Jan Maarten van Dijl, Emma L Denham
The multidrug ABC transporter BmrC/BmrD of Bacillus subtilis is regulated via a ribosome-mediated transcriptional attenuation mechanism.
Nucleic Acids Res: 2014, 42(18);11393-407
[PubMed:25217586] [WorldCat.org] [DOI] (I p)

Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675] [WorldCat.org] [DOI] (I p)