GerAB

• Description: nutrient receptor, germination response to L-alanine
  
  

Gene name	gerAB
Synonyms
Essential	no
Product	nutrient receptor
Function	germination response to L-alanine
Gene expression levels in SubtiExpress: gerAB
Interactions involving this protein in SubtInteract: GerAB
MW, pI	41 kDa, 9.601
Gene length, protein length	1095 bp, 365 aa
Immediate neighbours	gerAA, gerAC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigF regulon, SigG regulon, SpoVT regulon

The gene

Basic information

• Locus tag: BSU33060

Database entries

• BsubCyc: BSU33060

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:
  • amino acid, polyamine, organocation (APC) superfamily of transporters, TC 2.A.3

• Paralogous protein(s): GerBB, GerKB, YndE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GerAA-GerAB-GerAC (tentative receptor complex) PubMed
  • GerAB is part of the germinosome in the spore inner membrane PubMed

• Localization:
  • predicted to be an integral membrane protein with ten membrane-spanning helices PubMed

Database entries

• BsubCyc: BSU33060

• Structure:

• UniProt: P07869

• KEGG entry: [3]

• T.C. number: 2.A.3.9.1

Expression and regulation

• Operon: gerAA-gerAB-gerAC PubMed

• Expression browser: gerAB PubMed

• Sigma factor: SigG PubMed, SigF PubMed

• Regulation:
  • expressed during sporulation in the forespore (SigF, SigG, SpoVT) PubMed
  • expression level depends on sporulation conditions (medim composition, temperature) PubMed

• Regulatory mechanism:
  • SpoVT: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed