PhoA

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  • Description: alkaline phosphatase A

Gene name phoA
Synonyms phoAIV
Essential no
Product alkaline phosphatase A
Function aquisition of phosphate upon phosphoate starvation
Gene expression levels in SubtiExpress: phoA
MW, pI 50 kDa, 9.926
Gene length, protein length 1383 bp, 461 aa
Immediate neighbours spoVR, lytE
Sequences Protein DNA DNA_with_flanks
Genetic context
PhoA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PhoA expression.png
























Categories containing this gene/protein

phosphate metabolism

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

  • Locus tag: BSU09410

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: A phosphate monoester + H2O = an alcohol + phosphate (according to Swiss-Prot)
  • Protein family: alkaline phosphatase family (according to Swiss-Prot)
  • Paralogous protein(s): PhoB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Marion Hulett, University of Illinois at Chicago, USA Homepage

Your additional remarks

References