MalS
Revision as of 11:29, 7 January 2014 by 134.76.70.252 (talk)
- Description: malate dehydrogenase (decarboxylating), forms a transhydrogenation cycle with YtsJ for balancing of NADPH
Gene name | malS |
Synonyms | |
Essential | no |
Product | malate dehydrogenase (decarboxylating) |
Function | malate utilization |
Gene expression levels in SubtiExpress: malS | |
Metabolic function and regulation of this protein in SubtiPathways: malS | |
MW, pI | 61 kDa, 4.895 |
Gene length, protein length | 1698 bp, 566 aa |
Immediate neighbours | ytzB, ytnP |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
utilization of specific carbon sources
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29880
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-malate + NAD+ = pyruvate + CO2 + NADH (according to Swiss-Prot) malate --> pyruvate
- Protein family: malic enzymes family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34389
- KEGG entry: [3]
- E.C. number: 1.1.1.38
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: GP1142 (spc) available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed