GerAC

• Description: lipoprotein, nutrient receptor, germination response to L-alanine
  
  

Gene name	gerAC
Synonyms
Essential	no
Product	nutrient receptor
Function	germination response to L-alanine
Gene expression levels in SubtiExpress: gerAC
Interactions involving this protein in SubtInteract: GerAC
MW, pI	42 kDa, 7.302
Gene length, protein length	1119 bp, 373 aa
Immediate neighbours	gerAB, liaR
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigF regulon, SigG regulon, SpoVT regulon

The gene

Basic information

• Locus tag: BSU33070

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: gerABKC lipoprotein family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • has an N-terminal signal sequence, lipidated on a Cys residue adjacent to the signal peptide PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GerAA-GerAB-GerAC (tentative receptor complex) PubMed
  • GerAC is part of the germinosome in the spore inner membrane PubMed
  • GerAC-Lgt to fix GerAC to diacylglycerol in the membrane PubMed

• Localization: cell membrane (according to Swiss-Prot)
  • outer surface of the inner spore membrane PubMed

Database entries

• Structure:

• UniProt: P07870

• KEGG entry: [3]

• E.C. number:

Additional information

• 1,100 molecules are present per spore PubMed

Expression and regulation

• Operon: gerAA-gerAB-gerAC PubMed

• Expression browser: gerAC PubMed

• Sigma factor: SigG PubMed, SigF PubMed

• Regulation:
  • expressed during sporulation in the forespore (SigF, SigG, SpoVT) PubMed
  • expression level depends on sporulation conditions (medim composition, temperature) PubMed

• Regulatory mechanism:
  • SpoVT: transcription repression PubMed

• Additional information:
  • 1,100 molecules are present per spore PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: