LevR

• Description: transcriptional activator of the levD-levE-levF-levG-sacC operon
  
  

Gene name	levR
Synonyms
Essential	no
Product	transcriptional activator, PRD-type (for SigL-dependent promoter)
Function	regulation of levan and fructose utilization
Gene expression levels in SubtiExpress: levR
Interactions involving this protein in SubtInteract: LevR
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	105 kDa, 5.943
Gene length, protein length	2814 bp, 938 aa
Immediate neighbours	levD, aapA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control, phosphoproteins

The LevR regulon:

• levD-levE-levF-levG-sacC

The gene

Basic information

• Locus tag: BSU27080

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: binding to the upstream activating sequence in front of the levD gene results in activation of transcription of the levD-levE-levF-levG-sacC operon, bining occurs in the presence of fructose

• Protein family: transcriptional antiterminator bglG family (according to Swiss-Prot), Attention: this is wrong: LicR is a transcription activator, the similarity to the BglG family is limited to the PTS-regulation domains

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • PtsH-LevR
  • LevE-LevR
  • LevR-SigL

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P23914

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: levR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: