RbsB

• Description: ribose ABC transporter (binding protein)
  
  

Gene name	rbsB
Synonyms
Essential	no
Product	ribose ABC transporter (binding protein)
Function	ribose uptake
Gene expression levels in SubtiExpress: rbsB
Interactions involving this protein in SubtInteract: RbsB
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	32 kDa, 6.138
Gene length, protein length	915 bp, 305 aa
Immediate neighbours	rbsC, ywsB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

AbrB regulon, CcpA regulon

The gene

Basic information

• Locus tag: BSU35960

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: bacterial solute-binding protein 2 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • RbsA(2)-(RbsC-RbsD)-RbsB PubMed

• Localization:
  • extracellular (signal peptide), lipid modification as retention signal PubMed
  • attached to the cell membrane (via RbsC-RbsD) PubMed

Database entries

• Structure: 2GX6 (from Escherichia coli k12 mutant, 54% identity, 71% similarity)

• UniProt: P36949

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rbsR-rbsK-rbsD-rbsA-rbsC-rbsB PubMed

• Expression browser: rbsB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (CcpA) PubMed
  • expressed upon transition into the stationary phase (AbrB) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: