SpoIIIE
Revision as of 10:17, 14 May 2013 by 134.76.70.252 (talk)
- Description: ATP-dependent DNA translocase, transports the forespore chromosome across the sporulation septum
Gene name | spoIIIE |
Synonyms | |
Essential | no |
Product | ATP-dependent DNA translocase required for chromosome
partitioning through the septum into the forespore |
Function | chromosome partition during sporulation |
Gene expression levels in SubtiExpress: spoIIIE | |
MW, pI | 86 kDa, 6.757 |
Gene length, protein length | 2361 bp, 787 aa |
Immediate neighbours | ylzJ, ymfC |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
DNA condensation/ segregation, sporulation/ other, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16800
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- transports the forespore chromosome across the sporulation septum PubMed
- translocates septum-entrapped DNA only when septum closure precedes complete segregation of chromosomes PubMed
- the two DNA translocases SftA and SpoIIIE synergistically affect chromosome dimer resolution presumably by positioning the dif sites in close proximity, before or after completion of cell division, respectively PubMed
- Protein family:
- Paralogous protein(s): SftA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: transmembrane domain mediates dynamic localization to active division sites PubMed
Database entries
- Structure:
- UniProt: P21458
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: spoIIIE PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Christine Kaimer, Peter L Graumann
Players between the worlds: multifunctional DNA translocases.
Curr Opin Microbiol: 2011, 14(6);719-25
[PubMed:22047950]
[WorldCat.org]
[DOI]
(I p)
Original publications