YkuV

• Description: thiol disulfide oxidoreductase
  
  

Gene name	ykuV
Synonyms
Essential	no
Product	thiol disulfide oxidoreductase
Function	protection of proteins against oxidative damage
Gene expression levels in SubtiExpress: ykuV
MW, pI	17 kDa, 6.333
Gene length, protein length	459 bp, 153 aa
Immediate neighbours	ykuU, rok
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

• Locus tag: BSU14230

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 2B5X (reduced form), 2B5Y (oxidized form)

• UniProt: O31699

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ykuU-ykuV PubMed

• Expression browser: ykuV PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Xinxin Zhang, Yunfei Hu, Xianrong Guo, Ewen Lescop, You Li, Bin Xia, Changwen Jin
The Bacillus subtilis YkuV is a thiol:disulfide oxidoreductase revealed by its redox structures and activity.
J Biol Chem: 2006, 281(12);8296-304
[PubMed:16418167] [WorldCat.org] [DOI] (P p)