SleB

• Description: spore cortex-lytic enzyme
  
  

Gene name	sleB
Synonyms	ypeA
Essential	no
Product	spore cortex-lytic enzyme
Function	degration of the spore cortex, germination
Gene expression levels in SubtiExpress: sleB
MW, pI	33 kDa, 9.506
Gene length, protein length	915 bp, 305 aa
Immediate neighbours	ypeB, prsW
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigG regulon

The gene

Basic information

• Locus tag: BSU22930

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: sleB family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • contains a signal peptide PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • outer surface of the inner spore membrane PubMed

Database entries

• Structure:

• UniProt: P50739

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sleB-ypeB PubMed

• Expression browser: sleB PubMed

• Sigma factor: SigG PubMed

• Regulation:
  • expressed late during sporulation in the forespore (SigG) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1G21 ( sleB::spec), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: