YkuQ

• Description: similar to tetrahydrodipicolinate succinylase
  
  

Gene name	ykuQ
Synonyms
Essential	yes PubMed
Product	similar to tetrahydrodipicolinate succinylase
Function	biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: ykuQ
Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr
MW, pI	24 kDa, 4.678
Gene length, protein length	708 bp, 236 aa
Immediate neighbours	ykuP, ykuR
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, essential genes, biosynthesis/ acquisition of amino acids

The gene

Basic information

• Locus tag: BSU14180

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Acetyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H₂O = CoA + L-2-acetamido-6-oxoheptanedioate (according to Swiss-Prot)

• Protein family: transferase hexapeptide repeat family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3R8Y (from Bacillus anthracis, 80% identity, 96% similarity)

• UniProt: O34981

• KEGG entry: [2]

• E.C. number: 2.3.1.89

Expression and regulation

• Operon:

• Expression browser: ykuQ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: