RNases

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RNases are involved in the processing and degradation of the different classes of mRNAs, tRNAs, rRNAs and small RNAs

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Related categories

RNA degradosome





Exoribonucleases

  • RNase J1: 5'-3' activity, does also have endonuclease activity

Endoribonucleases

  • RNase J1: ssRNA endonuclease, does also have exonuclease activity
  • RNase J2: ssRNA endonuclease, may also have exonuclease activity

Labs working on RNases

Key original publications

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)

Reviews on RNases in Bacillus subtilis

Additional reviews: PubMed

Brian C Jester, Pascale Romby, Efthimia Lioliou
When ribonucleases come into play in pathogens: a survey of gram-positive bacteria.
Int J Microbiol: 2012, 2012;592196
[PubMed:22550495] [WorldCat.org] [DOI] (I p)

Inês Jesus Silva, Margarida Saramago, Clémentine Dressaire, Susana Domingues, Sandra Cristina Viegas, Cecília Maria Arraiano
Importance and key events of prokaryotic RNA decay: the ultimate fate of an RNA molecule.
Wiley Interdiscip Rev RNA: 2011, 2(6);818-36
[PubMed:21976285] [WorldCat.org] [DOI] (I p)

Ciarán Condon, David H Bechhofer
Regulated RNA stability in the Gram positives.
Curr Opin Microbiol: 2011, 14(2);148-54
[PubMed:21334965] [WorldCat.org] [DOI] (I p)

Flore Sinturel, Olivier Pellegrini, Song Xiang, Liang Tong, Ciarán Condon, Lionel Bénard
Real-time fluorescence detection of exoribonucleases.
RNA: 2009, 15(11);2057-62
[PubMed:19767421] [WorldCat.org] [DOI] (I p)



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