yhaM

yhaM
168

RNase, 3 5 exoribonuclease

Locus
BSU_09930
Molecular weight
35.53 kDa
Isoelectric point
5.85
Protein length
314 aaSequenceBlast
Gene length
945 bpSequenceBlast
Function
RNA degradation
Product
RNase YhaM
Essential
no
Synonyms
yhaM
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3481 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,069,042  1,069,986
The protein
Catalyzed reaction/ biological activity
3'-5' exoribonuclease
Protein family
YhaM family (single member, according to UniProt)
Domains
HD domain (aa 163-297) (according to UniProt)
Structure
O07521 (AlphaFold)
Localization
cytoplasm (Homogeneous) PubMed
Additional information
subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and Regulation
Operons
Genes
yhaO-sbcE-yhaM
Description
PubMed
Regulation
induced by DNA damage (LexA) PubMed
Regulatory mechanism
LexA: repression, PubMed, in lexA regulon
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yhaO→yhaM

2025-03-15 20:35:18

Bzhu

124

0fb329721ceeda68b6f68eed40be379aa5951941

BCA89E0E7644FD35258E73A933737E90BFD8B07E

Biological materials
Mutant
MGNA-B499 (yhaM::erm), available at the NBRP B. subtilis, Japan
BKE09930 (yhaM::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCTATTAAAGCTCCCTC,  downstream forward: _UP4_TAACTTAAAAAGGACTGATG
BKK09930 (yhaM::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCTATTAAAGCTCCCTC,  downstream forward: _UP4_TAACTTAAAAAGGACTGATG
Labs working on this gene/protein
David Bechhofer, Mount Sinai School, New York, USA Laboratories and Programs/Bechhofer Laboratory?citype=Physician&ciid=Bechhofer David H 1255565 Homepage
References
Reviews
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Original Publications
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6D585EB5E56A1E5C1C31680D960043BA08C817E2

Page visits: 4616

Time of last update: 2025-04-03 05:40:36

Author of last update: Jstuelk