PhrI

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Gene name phrI
Synonyms
Essential no
Product phosphatase (RapI) regulator
Function control of the transfer of the
mobile genetic element ICEBs1
Interactions involving this protein in SubtInteract: PhrI
MW, pI 4 kDa, 8.907
Gene length, protein length 117 bp, 39 aa
Immediate neighbours rapI, yddM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PhrI context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

protein modification, transcription factors and their control, quorum sensing, mobile genetic elements, short peptides

This gene is a member of the following regulons

SigH regulon

The gene

Basic information

  • Locus tag: BSU05020

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds RapI and inhibits its activity, this results in contiuned repression of the genes for the transfer of the mobile genetic element ICEBs1 by ImmR PubMed
  • Protein family: phr family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jennifer M Auchtung, Catherine A Lee, Katherine L Garrison, Alan D Grossman
Identification and characterization of the immunity repressor (ImmR) that controls the mobile genetic element ICEBs1 of Bacillus subtilis.
Mol Microbiol: 2007, 64(6);1515-28
[PubMed:17511812] [WorldCat.org] [DOI] (P p)

R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295] [WorldCat.org] [DOI] (P p)