AldX

• Description: aldehyde dehydrogenase (NAD)
  
  

Gene name	aldX
Synonyms	yxaS, yxbE
Essential	no
Product	aldehyde dehydrogenase (NAD)
Function	unknown
MW, pI	49 kDa, 4.844
Gene length, protein length	1335 bp, 445 aa
Immediate neighbours	yxbF, yxbD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

poorly characterized/ putative enzymes

The gene

Basic information

• Locus tag: BSU39860

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: An aldehyde + NAD⁺ + H₂O = an acid + NADH (according to Swiss-Prot)

• Protein family: aldehyde dehydrogenase family (according to Swiss-Prot)

• Paralogous protein(s): YfmT, AldY, YcbD, GabD, GbsA, DhaS, IolA, PutC, RocA, YwdH

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3RHH (from from Bacillus halodurans C-125 complexed with NADP, 29% identity, 61% similarity)

• UniProt: P46329

• KEGG entry: [3]

• E.C. number: 1.2.1.3

Expression and regulation

• Operon: aldX PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ken-Ichi Yoshida, Izumi Ishio, Eishi Nagakawa, Yoshiyuki Yamamoto, Mami Yamamoto, Yasutaro Fujita
Systematic study of gene expression and transcription organization in the gntZ-ywaA region of the Bacillus subtilis genome.
Microbiology (Reading): 2000, 146 ( Pt 3);573-579
[PubMed:10746760] [WorldCat.org] [DOI] (P p)