FlgK

• Description: flagellar hook-associated protein 1 (HAP1)
  
  

Gene name	flgK
Synonyms
Essential	no
Product	flagellar hook-associated protein 1 (HAP1)
Function	movement and chemotaxis
MW, pI	54 kDa, 4.375
Gene length, protein length	1521 bp, 507 aa
Immediate neighbours	flgL, yvyG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

ComK regulon, DegU regulon, SigD regulon

The gene

Basic information

• Locus tag: BSU35410

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: flagella basal body rod proteins family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • extracellular (no signal peptide) PubMed

Database entries

• Structure:

• UniProt: P39810

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • comFA-comFB-comFC-yvyF-flgM-yvyG-flgK-flgL PubMed
  • yvyF-flgM-yvyG-flgK-flgL PubMed
  • flgM-yvyG-flgK-flgL PubMed

• Sigma factor:
  • comFA: SigA PubMed
  • yvyF: SigD PubMed
  • flgM: SigD PubMed

• Regulation:

• Regulatory mechanism:
  • ComK: transcription activation PubMed
  • flgM: DegU-P: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

D B Mirel, P Lauer, M J Chamberlin
Identification of flagellar synthesis regulatory and structural genes in a sigma D-dependent operon of Bacillus subtilis.
J Bacteriol: 1994, 176(15);4492-500
[PubMed:8045879] [WorldCat.org] [DOI] (P p)

J A Londoño-Vallejo, D Dubnau
comF, a Bacillus subtilis late competence locus, encodes a protein similar to ATP-dependent RNA/DNA helicases.
Mol Microbiol: 1993, 9(1);119-31
[PubMed:8412657] [WorldCat.org] [DOI] (P p)