LiaH

• Description: resistance against oxidative stress and cell wall antibiotics (such as daptamycin)
  
  

Gene name	liaH
Synonyms	yvqH
Essential	no
Product	unknown
Function	resistance against oxidative stress and cell wall antibiotics
MW, pI	25 kDa, 6.172
Gene length, protein length	675 bp, 225 aa
Immediate neighbours	liaG, liaI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU33120

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: pspA/IM30 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: forms large oligomeric rings with a nine-fold rotational symmetry PubMed

• Localization:

Database entries

• Structure:

• UniProt: O32201

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: liaI-liaH-liaG-liaF-liaS-liaR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by bacitracin (LiaR) PubMed
  • repressed during logarithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • LiaR: transcription activation PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: