SpoVAD
- Description: essential for the uptake of the 1:1 chelate of pyridine-2,6-dicarboxylic acid (DPA(2,6)) and Ca(2+) into developing spores, likely germination protein
| Gene name | spoVAD |
| Synonyms | |
| Essential | no |
| Product | binding protein for DPA |
| Function | likely germination protein |
| Gene expression levels in SubtiExpress: spoVAD | |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr | |
| MW, pI | 35 kDa, 5.243 |
| Gene length, protein length | 1014 bp, 338 aa |
| Immediate neighbours | spoVAEB, spoVAC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
germination, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23410
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- maybe involved in spore germination PubMed
- binding of both DPA(2,6) and Ca(2+)-DPA(2,6) PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- outer surface of the inner spore membrane PubMed
Database entries
- Structure: 3LM6
- UniProt: P40869
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Peter Setlow, University of Connecticut Health Center, USA
Your additional remarks
References
Additional publications: PubMed
