Gdh

• Description: glucose 1-dehydrogenase (NAD)
  
  

Gene name	gdh
Synonyms
Essential	no
Product	glucose 1-dehydrogenase (NAD)
Function	germination
MW, pI	27 kDa, 5.082
Gene length, protein length	783 bp, 261 aa
Immediate neighbours	glcU, ycnI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

germination

This gene is a member of the following regulons

SigG regulon, SpoVT regulon

The gene

Basic information

• Locus tag: BSU03930

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Beta-D-glucose + NAD(P)⁺ = D-glucono-1,5-lactone + NAD(P)H (according to Swiss-Prot)

• Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P12310

• KEGG entry: [3]

• E.C. number: 1.1.1.47

Expression and regulation

• Operon: glcU-gdh PubMed

• Sigma factor: SigG PubMed

• Regulation:
  • expressed during sporulation (SigG, SpoVT) PubMed

• Regulatory mechanism:
  • SpoVT: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: