MalR
- Description: two-component response regulator, regulation of malate uptake
Gene name | malR |
Synonyms | yufM |
Essential | no |
Product | two-component response regulator |
Function | regulation of malate uptake |
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
MW, pI | 26 kDa, 5.976 |
Gene length, protein length | 705 bp, 235 aa |
Immediate neighbours | malK, yufN |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU31530
Phenotypes of a mutant
unable to use malate as the single carbon source PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
Categories containing this gene/protein
utilization of specific carbon sources, transcription factors and their control, phosphoproteins
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Genes/ operons controlled by MalR
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated by MalK on an Asp residue
- Cofactor(s):
- Effectors of protein activity: phosphorylation likely affects DNA-binding activity
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O05251
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France
Your additional remarks
References