CsfB

• Description: forespore-specific protein, inhibitor of SigG and of SigE
  
  

Gene name	csfB
Synonyms	gin, yaaM
Essential	no
Product	inhibitor of SigG and SigE
Function	control of SigG and SigE activity
Gene expression levels in SubtiExpress: csfB
Interactions involving this protein in SubtInteract: CsfB
MW, pI	7 kDa, 7.671
Gene length, protein length	192 bp, 64 aa
Immediate neighbours	rrnA-5S, xpaC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sigma factors and their control, sporulation proteins

This gene is a member of the following regulons

SigF regulon, SigK regulon

The gene

Basic information

• Locus tag: BSU00240

Phenotypes of a mutant

• premature activation of SigG PubMed

Database entries

• BsubCyc: BSU00240

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: inhibitor of SigG PubMed1 PubMed2

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • CsfB-SigG to inhibit SigG activity PubMed
  • CsfB-SigE to inhibit SigE activity PubMed

• Localization: forespore and mother cell PubMed

Database entries

• BsubCyc: BSU00240

• Structure:

• UniProt: P37534

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: csfB PubMed

• Expression browser: csfB PubMed

• Sigma factor:
  • SigF PubMed, SigK PubMed

• Regulation:
  • expressed early during sporulation in the forespore (SigF) PubMed
  • expressed after completion of forespore engulfment in the mother cell (SigK) PubMed
• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: