PstA

• Description: phosphate ABC transporter (permease)
  
  

Gene name	pstA
Synonyms	yqgI, yzmD
Essential	no
Product	phosphate ABC transporter (permease)
Function	high-affinity phosphate uptake
Gene expression levels in SubtiExpress: pstA
Interactions involving this protein in SubtInteract: PstA
MW, pI	31 kDa, 9.303
Gene length, protein length	882 bp, 294 aa
Immediate neighbours	pstBA, pstC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, phosphate metabolism, membrane proteins

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

• Locus tag: BSU24970

Database entries

• BsubCyc: BSU24970

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: CysTW subfamily (according to Swiss-Prot)

• Paralogous protein(s): PstC

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • (PstBA-PstBB)-(PstA-PstC)-PstS PubMed

• Localization: membrane protein PubMed

Database entries

• BsubCyc: BSU24970

• Structure:

• UniProt: P46340

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: pstS-pstC-pstA-pstBA-pstBB PubMed

• Expression browser: pstA PubMed

• Sigma factor: SigA PubMed

• Regulation: expressed under conditions of phosphate limitation (5000-fold induced) (PhoP) PubMed

• Regulatory mechanism:
  • PhoP: transcription activation PubMed

• Additional information:
  • mRNA processing between pstS and pstC to maintain higher concentrations of PstS relative to other components of the ABC transporter PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Marion Hulett, University of Illinois at Chicago, USA Homepage