YqcG

• Description: toxin
  
  

Gene name	yqcG
Synonyms
Essential	no
Product	toxin
Function	unknown
Gene expression levels in SubtiExpress: yqcG
Interactions involving this protein in SubtInteract: YqcG
MW, pI	59 kDa, 8.813
Gene length, protein length	1593 bp, 531 aa
Immediate neighbours	yqzI, yqcF
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, Skin element

This gene is a member of the following regulons

AbrB regulon, Spo0A regulon

The gene

Basic information

• Locus tag: BSU25860

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: UPF0720 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YqcG-YqcF PubMed

• Localization:

Database entries

• Structure:

• UniProt: P45942

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yqcG-yqcF (according to DBTBS)

• Expression browser: yqcG PubMed

• Sigma factor:

• Regulation:
  • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • strongly repressed in response to glucose starvation in M9 medium PubMed

• Regulatory mechanism:
  • Spo0A: transcription activation PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Laura E Holberger, Fernando Garza-Sánchez, James Lamoureux, David A Low, Christopher S Hayes
A novel family of toxin/antitoxin proteins in Bacillus species.
FEBS Lett: 2012, 586(2);132-6
[PubMed:22200572] [WorldCat.org] [DOI] (I p)

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)