GerAB

• Description: nutrient receptor, germination response to L-alanine
  
  

Gene name	gerAB
Synonyms
Essential	no
Product	nutrient receptor
Function	germination response to L-alanine
Gene expression levels in SubtiExpress: gerAB
Interactions involving this protein in SubtInteract: GerAB
MW, pI	41 kDa, 9.601
Gene length, protein length	1095 bp, 365 aa
Immediate neighbours	gerAA, gerAC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigF regulon, SigG regulon, SpoVT regulon

The gene

Basic information

• Locus tag: BSU33060

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GerAA-GerAB-GerAC (tentative receptor complex) PubMed
  • GerAB is part of the germinosome in the spore inner membrane PubMed

• Localization:
  • predicted to be an integral membrane protein with ten membrane-spanning helices PubMed

Database entries

• Structure:

• UniProt: P07869

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerAA-gerAB-gerAC PubMed

• Expression browser: gerAB PubMed

• Sigma factor: SigG PubMed, SigF PubMed

• Regulation:
  • expressed during sporulation in the forespore (SigF, SigG, SpoVT) PubMed
  • expression level depends on sporulation conditions (medim composition, temperature) PubMed

• Regulatory mechanism:
  • SpoVT: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed