RbsB

• Description: ribose ABC transporter (binding protein)
  
  

Gene name	rbsB
Synonyms
Essential	no
Product	ribose ABC transporter (binding protein)
Function	ribose uptake
Interactions involving this protein in SubtInteract: RbsB
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	32 kDa, 6.138
Gene length, protein length	915 bp, 305 aa
Immediate neighbours	rbsC, ywsB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

ABC transporters, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

AbrB regulon, CcpA regulon

The gene

Basic information

• Locus tag: BSU35960

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: bacterial solute-binding protein 2 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: RbsA(2)-(RbsC-RbsD)-RbsB PubMed

• Localization: extracellular (signal peptide), lipid modification as retention signal PubMed, attached to the cell membrane (via RbsC-RbsD) PubMed

Database entries

• Structure: 2GX6 (from Escherichia coli k12 mutant, 54% identity, 71% similarity)

• UniProt: P36949

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rbsR-rbsK-rbsD-rbsA-rbsC-rbsB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (CcpA) PubMed
  • expressed upon transition into the stationary phase (AbrB) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: