Difference between revisions of "CsfB"

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* '''Description:''' forespore-specific protein, controls SigG activation <br/><br/>
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* '''Description:''' forespore-specific protein, inhibitor of [[SigG]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || forespore-specific protein
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|style="background:#ABCDEF;" align="center"| '''Product''' || inhibitor of [[SigG]]
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of SigG activation
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigG]] activity
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 7 kDa, 7.671   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 7 kDa, 7.671   
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' prevents premature activation of SigG [http://www.ncbi.nlm.nih.gov/sites/entrez/17921305 PubMed]
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* '''Catalyzed reaction/ biological activity:''' inhibitor of [[SigG]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17921305 PubMed1] [http://www.ncbi.nlm.nih.gov/sites/entrez/19497328 PubMed2]
 +
 
  
 
* '''Protein family:'''
 
* '''Protein family:'''
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
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* '''Interactions:''' [[CsfB]]-[[SigG]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19497328 PubMed]
  
* '''Localization:'''
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* '''Localization:''' forespore
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 18:30, 7 June 2009

  • Description: forespore-specific protein, inhibitor of SigG

Gene name csfB
Synonyms yaaM
Essential no
Product inhibitor of SigG
Function control of SigG activity
MW, pI 7 kDa, 7.671
Gene length, protein length 192 bp, 64 aa
Immediate neighbours rrnA-5S, xpaC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CsfB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU00240

Phenotypes of a mutant

premature activation of SigG PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution


  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: forespore

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: csfB
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Wang et al. (2006) The forespore line of gene expression in Bacillus subtilis. J. Mol. Biol. 358: 16-37. PubMed
  2. Chary et al. (2007) Expression of the sigmaF-directed csfB locus prevents premature appearance of sigmaG activity during sporulation of Bacillus subtilis.J. Bacteriol. 189: 8754-8757. PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed