Difference between revisions of "T-box"
(→Genes controlled by T-box elements) |
|||
| Line 15: | Line 15: | ||
* Induction by glycine limitation | * Induction by glycine limitation | ||
| − | ** ''[[glyQ]]-[[glyS]]'' | + | ** ''[[glyA]], [[glyQ]]-[[glyS]]'' |
* Induction by histidine limitation | * Induction by histidine limitation | ||
| Line 21: | Line 21: | ||
* Induction by isoleucine limitation | * Induction by isoleucine limitation | ||
| − | ** ''[[ileS]]'' | + | ** ''[[ileS]]'', ''[[ilvB]]-[[ilvH]]-[[ilvC]]-[[leuA]]-[[leuA]]-[[leuC]]-[[leuD]]'' |
* Induction by leucine limitation | * Induction by leucine limitation | ||
| − | ** ''[[leuS]]'' | + | ** ''[[leuS]]'', ''[[ilvB]]-[[ilvH]]-[[ilvC]]-[[leuA]]-[[leuA]]-[[leuC]]-[[leuD]]'' |
| + | |||
| + | * Induction by methionine limitation | ||
| + | ** ''[[metE]]'', ''[[yxjG]], [[yjcI]]-[[yjcJ]], [[yitJ]]-[[yitI]]-[[yitH]]'' | ||
* Induction by phenyalanine limitation | * Induction by phenyalanine limitation | ||
| Line 42: | Line 45: | ||
* Induction by valine limitation | * Induction by valine limitation | ||
| − | ** ''[[valS]]'' | + | ** ''[[valS]]'', ''[[ilvB]]-[[ilvH]]-[[ilvC]]-[[leuA]]-[[leuA]]-[[leuC]]-[[leuD]]'' |
==Reviews on T-box regulation== | ==Reviews on T-box regulation== | ||
<pubmed> 19258532,7527891, 8348614,17381302 </pubmed> | <pubmed> 19258532,7527891, 8348614,17381302 </pubmed> | ||
Revision as of 04:26, 28 May 2009
The T-box element is an RNA switch that controls genes involved in amino acid metabolism.
In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid.
Genes controlled by T-box elements
- Induction by alanine limitation
- Induction by serine limitation
Reviews on T-box regulation
Ana Gutiérrez-Preciado, Tina M Henkin, Frank J Grundy, Charles Yanofsky, Enrique Merino
Biochemical features and functional implications of the RNA-based T-box regulatory mechanism.
Microbiol Mol Biol Rev: 2009, 73(1);36-61
[PubMed:19258532]
[WorldCat.org]
[DOI]
(I p)
T M Henkin, F J Grundy
Sensing metabolic signals with nascent RNA transcripts: the T box and S box riboswitches as paradigms.
Cold Spring Harb Symp Quant Biol: 2006, 71;231-7
[PubMed:17381302]
[WorldCat.org]
[DOI]
(P p)
T M Henkin
tRNA-directed transcription antitermination.
Mol Microbiol: 1994, 13(3);381-7
[PubMed:7527891]
[WorldCat.org]
[DOI]
(P p)
F J Grundy, T M Henkin
tRNA as a positive regulator of transcription antitermination in B. subtilis.
Cell: 1993, 74(3);475-82
[PubMed:8348614]
[WorldCat.org]
[DOI]
(P p)
