Difference between revisions of "MntA"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[mntA]]-[[mntB]]-[[mntC]]-[[mntD]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/12950915 PubMed] |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] |
| − | * '''Regulation:''' | + | * '''Regulation:''' repressed by Mn(2+) ([[MntR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12950915 PubMed] |
| − | * '''Regulatory mechanism:''' | + | * '''Regulatory mechanism:''' MntR: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12950915 PubMed] |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 115: | Line 115: | ||
=Labs working on this gene/protein= | =Labs working on this gene/protein= | ||
| + | |||
| + | John Helmann, Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage] | ||
=Your additional remarks= | =Your additional remarks= | ||
Revision as of 09:53, 24 May 2009
- Description: manganese ABC transporter (membrane protein)
| Gene name | mntA |
| Synonyms | ytgA |
| Essential | yes PubMed |
| Product | manganese ABC transporter (membrane protein) |
| Function | manganese uptake |
| MW, pI | 33 kDa, 6.162 |
| Gene length, protein length | 918 bp, 306 aa |
| Immediate neighbours | mntB, menC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: bacterial solute-binding protein 9 family (according to Swiss-Prot)
- Paralogous protein(s): YcdH
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot), extracellular (signal peptide) PubMed
Database entries
- Structure:
- Swiss prot entry: O34385
- KEGG entry: BSU30770
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism: MntR: transcription repression PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
Your additional remarks
References
- Voigt et al. (2009) Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis. J Mol Microbiol Biotechnol. 16: 53-68 PubMed
- Que Q, Helmann JD. (2000) Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins. Mol Microbiol. Mar;35(6): 1454-68. PubMed
- Thomaides, H. B., Davison, E. J., Burston, L., Johnson, H., Brown, D. R., Hunt, A. C., Errington, J., and Czaplewski, L. (2007) Essential bacterial functions encoded by gene pairs. J Bacteriol 189, 591-602. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
