mntD

mntD
168

manganese ABC transporter (permease)

Locus
BSU_30740
Molecular weight
30.91 kDa
Isoelectric point
6.31
Protein length
295 aaSequenceBlast
Gene length
888 bpSequenceBlast
Function
manganese uptake
Product
manganese ABC transporter (permease)
Essential
no
Synonyms
mntD, ytgD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1108 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,142,077 → 3,142,964
The protein
Protein family
ABC-3 integral membrane protein family (with MntC and ZnuB, according to UniProt)
Structure
O34500 (AlphaFold)
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
mntA-mntB-mntC-mntD
Description
PubMed
Regulation
repressed at high Mn(II) concentrations (MntR) PubMed
Regulatory mechanism
MntR: repression, PubMed, in mntR regulon
Additional information
A ncRNA is predicted between 'mntA' and 'menC' PubMed
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mntA→mntD

2025-03-27 20:02:48

ghost

80

6e445d5dd4775b53ffb927e076588a54d6db5b65

22EB6DB7C3644A1DB5E7DC4F2D2D0BF8933A5D53

Biological materials
Mutant
MGNA-A288 (ytgD::erm), available at the NBRP B. subtilis, Japan
BKE30740 (ΔmntD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CTTCAAAACTCATTTGCGAT,  downstream forward: _UP4_GGCTGATGCAGCTCTTTCTT
BKK30740 (ΔmntD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CTTCAAAACTCATTTGCGAT,  downstream forward: _UP4_GGCTGATGCAGCTCTTTCTT
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
References
Reviews
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Original Publications
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F7DA077FE47DBB409BE2B1D9F12A9D719C246166

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Time of last update: 2025-03-31 17:09:10

Author of last update: Jstuelk